The Baker Institute’s Metabolomics Laboratory uses state-of-the-art tandem mass spectrometry to obtain metabolic profiles (primarily lipids and fats) from cell and animal models, in addition to clinically relevant human samples.
This technology can help to better understand the metabolic dysregulation associated with conditions including obesity, diabetes and cardiovascular disease and its relationship to the pathogenesis of these disease states.
The platform has developed a targeted lipidomics approach that enables quantification of more than 750 lipid species across 30 lipid classes and subclasses. The analysis is performed by liquid chromatography tandem mass spectrometry.
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